Side effects of antihistamines that make you drowsy can include: sleepiness (drowsiness) and reduced co-ordination, reaction speed and judgement – do not drive or use machinery after taking these antihistamines. dry mouth. blurred vision. difficulty peeing. Side effects of non-drowsy antihistamines can include: headache. Experts say skip antihistamines. Dana Benson. 713-798-8267. Houston, TX - Jun 28, 2021. Share this article. For people who take an antihistamine such as Benadryl for a cold or allergies, drowsiness is often a welcome side effect. But a Baylor College of Medicine sleep expert cautions against turning to this type of medication as a sleep aid.Dizziness Nausea or vomiting Loss of appetite Constipation Increased chest congestion Headache Excitability (especially in children) Nervousness Benadryl can impair mental and motor functioning, as well as your performance at work or school. It can also impair a person’s ability to operate a motor vehicle or other potentially dangerous equipment.Jun 23, 2009 · The most common side effect is drowsiness, causing mild disorientation or dementia. An elderly person may fall asleep during normal activities. This sedating effect can cause unsteadiness. A person over 60 should get up slowly from a sitting or prone position to avoid fainting. If you take an anti-anxiety drug, it is not advisable to use ... and readily penetrates the blood-brain-barrier. Thus side effects such as grogginess, drowsiness, and memory loss are common. Diphenhydramine is also used for motion sickness and extrapyramidal symptoms in Parkinson’s disease patients. Potential harm to the brain: Long-term anticholinergic use has been associated with increasedNov 15, 2019 · Central side effects. Since these actions are disrupted by sedating antihistamines, these drugs produce sedation, drowsiness, tiredness, lack of concentration, difficulty in learning and memory ... Jun 8, 2022 · Sleep aids: The options. Sleep aids available without a prescription are widely available. Common choices and the potential side effects include: Diphenhydramine (Benadryl). Diphenhydramine is a sedating antihistamine. Side effects might include daytime drowsiness, dry mouth, constipation and urinary retention. Doxylamine (Unisom). Aug 23, 2021 · Symptoms can be mild or serious and can include: skin rash. itchiness. flushing (temporary warmth, redness, or deepening of skin color) swelling under your skin, typically in your eyelids, lips, hands, or feet. swelling of your mouth, tongue, or throat, which can make it hard to breathe. Jul 7, 2022 · Advertisement constipation. blurred vision. memory problems and dementia (especially in seniors) anxiety. dependence. What are the side effects of taking Benadryl every night? SIDE EFFECTS: Drowsiness, dizziness, constipation, stomach upset, blurred vision, or dry mouth/nose/throat may occur. If any of these effects persist or worsen, tell your doctor or pharmacistRead More → Answer (1 of 2): Here is one long term study: “These drugs are called anticholinergics, among them the first-generation antihistamines that are now marketed as sleep aids.Side effects of antihistamines that make you drowsy can include: sleepiness (drowsiness) and reduced co-ordination, reaction speed and judgement – do not drive or use machinery after taking these antihistamines. dry mouth. blurred vision. difficulty peeing. Side effects of non-drowsy antihistamines can include: headache. Some dosage forms listed on this page may not apply to the brand name Benadryl Allergy. Summary. More frequent side effects include: sedated state and thickening of bronchial secretions. Continue reading for a comprehensive list of adverse effects. Applies to diphenhydramine: oral capsules and tablets, parenteral injection. Side effects include:Benadryl can cause some children to be hyperactive. OTC cough and cold medicine should not be given to children under the age of 4. Research has shown that these products do not work in children younger than 6 years old and can have serious side effects.The Major Antihistamine Effects of Diphenhydramine Prevents Histamine-Mediated: constriction of respiratory smooth muscle. rapid vasodilation in blood vessels. increased capillary permeability and subsequent edema. sensations of itching, pain, and “flare” formation. increase in heart rate and strength of contraction.May 13, 2021 · The active ingredient in Benadryl is called diphenhydramine. Like any medication, Benadryl has several side effects. Some of the most common are: feeling sleepy or drowsy. dry mouth or throat ... Diphenhydramine blocks the effects of histamine in your brain and this reduces symptoms. It enters the brain in large quantities and this can make you feel drowsy. Diphenhydramine also blocks the effects of another chemical called acetylcholine. This can help a cough or runny nose but can also cause side effects such as a dry mouth and dry nose.Jan 24, 2018 · Taking an over-the-counter sleep aid with diphenhydramine once in a while is generally not going to cause problems, other than a possible hangover the next day. Older people, however, can get confused when taking diphenhydramine because it also blocks a brain chemical called acetylcholine, which plays a big role in attention and short-term memory. May 8, 2019 · Answer. While Benadryl ( diphenhydramine) can safely be used once in a while as a sleep aid, long-term use is not recommended for multiple reasons. Even the intermittent use of Benadryl for sleep isn't generally recommended if you are elderly (over 65). Studies show that the elderly population doesn't metabolize Benadryl as quickly and are far ... Diphenhydramine blocks the effects of histamine in your brain and this reduces symptoms. It enters the brain in large quantities and this can make you feel drowsy. Diphenhydramine also blocks the effects of another chemical called acetylcholine. This can help a cough or runny nose but can also cause side effects such as a dry mouth and dry nose. Diphenhydramine, which is available as an over-the-counter medication, is a first-generation antihistamine that is used in a variety of conditions to treat and prevent dystonias, insomnia, pruritis, urticaria, vertigo, and motion sickness. It also possesses local anesthetic properties for those patients who have allergies to other, more commonly used local anesthetics; however, this is an off ...You may take an antihistamine every day to keep long-term allergy symptoms under control. Types of antihistamines. Second-generation antihistamine. If you take an antihistamine frequently or daily, your health care provider may recommend a second-generation antihistamine as they are less likely to cause side effects like sleepiness and fatigue ...The Major Antihistamine Effects of Diphenhydramine Prevents Histamine-Mediated: constriction of respiratory smooth muscle. rapid vasodilation in blood vessels. increased capillary permeability and subsequent edema. sensations of itching, pain, and “flare” formation. increase in heart rate and strength of contraction.Aug 25, 2021 · Examples of Viagra’s more commonly reported side effects include: headache. flushing (temporary warmth, redness, or deepening of skin color) stuffy nose. indigestion (upset stomach) mild vision ... Side effects of antihistamines that make you drowsy can include: sleepiness (drowsiness) and reduced co-ordination, reaction speed and judgement – do not drive or use machinery after taking these antihistamines. dry mouth. blurred vision. difficulty peeing. Side effects of non-drowsy antihistamines can include: headache.Diphenhydramine or : Benadryl (diphenhydramine) may cause sedation the next day (due to its long half-life), decreased alertness, diminished cognitive function, delirium, ... Read More. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help. 5k views Reviewed >2 years ago. Sep 14, 2022 · Benadryl helps reduce the effects of natural chemicals in the body called histamines. It is used to treat the side effects of an allergic reaction, including: Benadryl can be taken to relieve the symptoms of hayfever (seasonal allergies) and motion sickness. It can also be taken to induce sleep and treat certain symptoms of Parkinson's disease. Jun 5, 2019 · Moderate and Severe Benadryl Side Effects. If patients are using Benadryl for an allergic reaction, and experience any of the following moderate to severe Benadryl side effects they should consult their medical doctor or contact emergency medical services to minimize injury to their health: Contact and Atopic dermatitis ~1.0-10.0%; Confusion Jul 31, 2023 · Extrapyramidal side effects (EPS), commonly referred to as drug-induced movement disorders are among the most common adverse drug effects patients experience from dopamine-receptor blocking agents. It was first described in 1952 after chlorpromazine-induced symptoms resembling Parkinson disease.[1] A variety of movement phenotypes has since been described along the EPS spectrum, including ... Overdosing on diphenhydramine (Benadryl) can also lead to more serious side effects like severe confusion, seizures, low blood pressure, involuntary muscle spasms, hallucinations (seeing things that aren't there), and heart rhythm problems. In fact, the FDA released a warning to avoid high doses of diphenhydramine.Diphenhydramine (Benadryl) is a common over-the-counter allergy medication. It’s part of a class of drugs called anticholinergics that research has linked to dementia in older people.Take one to two 50mg tablets at least 30 minutes prior to bedtime. The maximum dose of two tablets works best for sleep. You can take Dramamine with or without food, but make sure you take a dose with a full glass of water 1 2. Swallow tablets whole; don't crush or chew. Plan on taking Dramamine four to six hours prior to waking for the next ...Diphenhydramine, which is available as an over-the-counter medication, is a first-generation antihistamine that is used in a variety of conditions to treat and prevent dystonias, insomnia, pruritis, urticaria, vertigo, and motion sickness. It also possesses local anesthetic properties for those patients who have allergies to other, more commonly used local anesthetics; however, this is an off ...Benadryl helps reduce the effects of natural chemicals in the body called histamines. It is used to treat the side effects of an allergic reaction, including: Benadryl can be taken to relieve the symptoms of hayfever (seasonal allergies) and motion sickness. It can also be taken to induce sleep and treat certain symptoms of Parkinson's disease.Jan 24, 2018 · Taking an over-the-counter sleep aid with diphenhydramine once in a while is generally not going to cause problems, other than a possible hangover the next day. Older people, however, can get confused when taking diphenhydramine because it also blocks a brain chemical called acetylcholine, which plays a big role in attention and short-term memory. Diphenhydramine, which is available as an over-the-counter medication, is a first-generation antihistamine that is used in a variety of conditions to treat and prevent dystonias, insomnia, pruritis, urticaria, vertigo, and motion sickness. It also possesses local anesthetic properties for those patients who have allergies to other, more commonly used local anesthetics; however, this is an off ...Potential Kidney Risks. Yes, long-term use of Benadryl can put strain on the kidneys, as it can build up in the system. This can cause toxicity and potentially lead to kidney damage. It's important to be aware of the potential side effects of long-term use and to consult a doctor if any symptoms arise.But it has quite a long list of possible side effects. In fact, the Canadian Society of Allergy and Clinical Immunology has given serious warnings about them, even for people. The organization issued a 2019 position statement about Benadryl. They advised against the drug because of the high risk of side effects and overdose. They said the drug ...Potential Kidney Risks. Yes, long-term use of Benadryl can put strain on the kidneys, as it can build up in the system. This can cause toxicity and potentially lead to kidney damage. It's important to be aware of the potential side effects of long-term use and to consult a doctor if any symptoms arise.Diphenhydramine blocks the effects of histamine in your brain and this reduces symptoms. It enters the brain in large quantities and this can make you feel drowsy. Diphenhydramine also blocks the effects of another chemical called acetylcholine. This can help a cough or runny nose but can also cause side effects such as a dry mouth and dry nose. A 2017 study revealed that 10% of adults aged 18-45 use OTC sleep aids while 17.5% of people 65 years and older do. Most over-the-counter options are considered safe when used occasionally—as long as the medication is compatible with any medical conditions you have and other medications you take. But when taken night after night, trouble can ...Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough, runny ...Diphenhydramine, which is available as an over-the-counter medication, is a first-generation antihistamine that is used in a variety of conditions to treat and prevent dystonias, insomnia, pruritis, urticaria, vertigo, and motion sickness. It also possesses local anesthetic properties for those patients who have allergies to other, more commonly used local anesthetics; however, this is an off ...Nov 24, 2022 · But it has quite a long list of possible side effects. In fact, the Canadian Society of Allergy and Clinical Immunology has given serious warnings about them, even for people. The organization issued a 2019 position statement about Benadryl. They advised against the drug because of the high risk of side effects and overdose. They said the drug ... Long-term use of Benadryl can also lead to constipation and confusion. Interactions. Benadryl containing diphenhydramine can interact with alcohol as both are central nervous system (CNS) depressants. Side effects such as drowsiness and dizziness may be enhanced when taking alcohol with diphenhydramine.While it may work to help you fall asleep for a few days, long-term use of Benadryl as a sleep-aid likely isn't effective and is associated with several side effects like next-day drowsiness. Additionally, the long-term use of drugs like Benadryl in those 65 years old and over is linked with an increased risk of dementia.Pay attention to the side effects of Benadryl, especially if you’re an older adult. The body responds differently to Benadryl as you get older. And you may develop side effects that were never a problem before. Benadryl is not intended to be used as a daily, long-term medication for sleep or other issues.Dear Alice, I've experimented with the abuse of Benadryl on a few occasions now and have been absolutely blown off to another world, I was just curious as to what the side affects, long or short-term, can look like, and what the dangers are of abusing this drug (acetaminophen free).While it may work to help you fall asleep for a few days, long-term use of Benadryl as a sleep-aid likely isn't effective and is associated with several side effects like next-day drowsiness. Additionally, the long-term use of drugs like Benadryl in those 65 years old and over is linked with an increased risk of dementia.While there are cases of misuse and abuse, withdrawal symptoms from Benadryl are rare, even with long term use. Nevertheless, Benadryl has strong anticholinergic effects, and there have been reports of 'anticholinergic withdrawal' in some individuals taking Benadryl for extended periods of time. Potential symptoms include:Oct 3, 2022 · Applies to diphenhydramine: oral capsules and tablets, parenteral injection. Side effects include: Sedation, sleepiness, dizziness, disturbed coordination, epigastric distress, thickening of bronchial secretions. Dec 1, 2022 · Section snippets Sedation. The sedation associated with diphenhydramine is one of the most acknowledged effects of this medication. Indeed, it is frequently used as a medication to treat insomnia. 3 The sedative effect of diphenhydramine is related to its easy penetration of the blood-brain barrier. 4 In the brain, diphenhydramine interferes with H 1 receptors, which causes drowsiness and ... The most common side effect is drowsiness, causing mild disorientation or dementia. An elderly person may fall asleep during normal activities. This sedating effect can cause unsteadiness. A person over 60 should get up slowly from a sitting or prone position to avoid fainting. If you take an anti-anxiety drug, it is not advisable to use ...Diphenhydramine is a type of medicine called an antihistamine. It is used in some allergy and sleep medicines. Overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. This article is for information only. DO NOT use it to treat or manage an actual overdose. January 19, 2022. By Harvard Health Publishing Staff. A report published in JAMA Internal Medicine several years ago highlighted a link between long-term use of anticholinergic medications like Benadryl and dementia. While this study and other observational studies have also found this association, it doesn't prove that these drugs cause dementia.Apr 24, 2023 · Long-term use may also lead to harmful side effects. The inability to fall or stay asleep can have a significant, negative impact on your mood, productivity, and overall health. Insomnia can also ... May 7, 2021 · There is evidence that the use of diphenhydramine among older adults or the elderly may result in serious side effects. This holds true esp. if you are older than age 65. The older a person becomes, the greater the risk of adverse effects. Benadryl is listed as potentially Inappropriate Medication in Older Adults ( also known as Beers criteria) Dec 1, 2022 · Section snippets Sedation. The sedation associated with diphenhydramine is one of the most acknowledged effects of this medication. Indeed, it is frequently used as a medication to treat insomnia. 3 The sedative effect of diphenhydramine is related to its easy penetration of the blood-brain barrier. 4 In the brain, diphenhydramine interferes with H 1 receptors, which causes drowsiness and ... Jul 27, 2017 · Take one to two 50mg tablets at least 30 minutes prior to bedtime. The maximum dose of two tablets works best for sleep. You can take Dramamine with or without food, but make sure you take a dose with a full glass of water 1 2. Swallow tablets whole; don't crush or chew. Plan on taking Dramamine four to six hours prior to waking for the next ... Applies to diphenhydramine: compounding powder, injectable solution, oral capsule, oral disintegrating strip, oral liquid, oral tablet, oral tablet chewable, oral tablet disintegrating. General The most commonly reported side effects included somnolence, dizziness, and incoordination.Feb 18, 2010 · One Benadryl per night seems to be enough to keep the ears dry & the resulting nausea at bay. I must admit that I'm not sure this is still even a problem for me. The last time I stopped to see if I still needed it was about 2 years ago. After 3 days, the dizziness/nausea/inner ear issues came back, so I promptly started taking the nightly ... Addiction and Misuse. Another cause of overdose is an addiction to Diphenhydramine. Patients can become addicted to Benadryl after taking it for an extended period or when it is used for recreational purposes. Side effects of Diphenhydramine overdose often cause long-term damage, which can be fatal to patients ingesting it.Jun 14, 2023 · The symptoms you have noticed are very likely the result of long-term heavy antihistamine use. Antihistamines tend to dry up the nose, which is why they are so effective in humans with allergic rhinitis, but the way they do that is by making the secretions thicker. In dogs, we are not worried much about a runny nose, but we are concerned about ... Long-term use of Benadryl can also lead to constipation and confusion. Interactions. Benadryl containing diphenhydramine can interact with alcohol as both are central nervous system (CNS) depressants. Side effects such as drowsiness and dizziness may be enhanced when taking alcohol with diphenhydramine. Nov 15, 2017 · Asthma. Car Sickness. Insomnia. Motion sickness. Reactions to Vaccines. Because one of the common side effect of Benadryl in dogs is drowsiness, your vet may use it to alleviate dog anxiety, particularly associated with traveling and motion sickness that may occur during plane rides or car trips. Besides having side effects including drowsiness, confusion, and urinary retention, a new study shows that frequent, long-term use of older antihistamines are associated with an increased risk of ...A 2017 study revealed that 10% of adults aged 18-45 use OTC sleep aids while 17.5% of people 65 years and older do. Most over-the-counter options are considered safe when used occasionally—as long as the medication is compatible with any medical conditions you have and other medications you take. But when taken night after night, trouble can ...Jul 5, 2023 · Benadryl is an antihistamine that can be used to treat allergic reactions, relieve motion sickness, as a sleep aid, and relieve some symptoms of Parkinson's disease. Sedation is a common side effect. 5. Tips. Benadryl may be taken with or without food. Take exactly as directed. Nov 15, 2017 · Asthma. Car Sickness. Insomnia. Motion sickness. Reactions to Vaccines. Because one of the common side effect of Benadryl in dogs is drowsiness, your vet may use it to alleviate dog anxiety, particularly associated with traveling and motion sickness that may occur during plane rides or car trips. Jun 5, 2019 · Moderate and Severe Benadryl Side Effects. If patients are using Benadryl for an allergic reaction, and experience any of the following moderate to severe Benadryl side effects they should consult their medical doctor or contact emergency medical services to minimize injury to their health: Contact and Atopic dermatitis ~1.0-10.0%; Confusion While there are cases of misuse and abuse, withdrawal symptoms from Benadryl are rare, even with long term use. Nevertheless, Benadryl has strong anticholinergic effects, and there have been reports of 'anticholinergic withdrawal' in some individuals taking Benadryl for extended periods of time. Potential symptoms include:This video examines the question and remark: Benadryl long term side effects! I WISH I had KNOWN! Benadryl is a common OTC medication and is also known as D...Sep 4, 2023 · Impaired concentration. Memory difficulties. Anxiety. Stomach disturbances. Nausea and vomiting. A dry mouth. Constipation. Liver problems, etc. In certain people, a paradoxical reaction to diphenhydramine is possible, meaning that the drug causes different symptoms than the intended ones. Answer From Eric J. Olson, M.D. It's unlikely you'll become dependent on zolpidem (Ambien). Ambien and similar sleep medications can be effective, and they're much less likely to be habit-forming than some other drugs sometimes prescribed for sleep problems — for example, benzodiazepines, such as alprazolam (Xanax), lorazepam (Ativan) or ...Apr 23, 2021 · Hives. Swelling and inflammation. Redness. Runny nose and eyes. Coughing. Sneezing. Anaphylactic reaction. One of the side effects of Benadryl is drowsiness, which can help to calm anxious dogs ... Hives. Swelling and inflammation. Redness. Runny nose and eyes. Coughing. Sneezing. Anaphylactic reaction. One of the side effects of Benadryl is drowsiness, which can help to calm anxious dogs ...Central side effects. Since these actions are disrupted by sedating antihistamines, these drugs produce sedation, drowsiness, tiredness, lack of concentration, difficulty in learning and memory ...Besides having side effects including drowsiness, confusion, and urinary retention, a new study shows that frequent, long-term use of older antihistamines are associated with an increased risk of ...There is evidence that the use of diphenhydramine among older adults or the elderly may result in serious side effects. This holds true esp. if you are older than age 65. The older a person becomes, the greater the risk of adverse effects. Benadryl is listed as potentially Inappropriate Medication in Older Adults ( also known as Beers criteria)Answer From Eric J. Olson, M.D. It's unlikely you'll become dependent on zolpidem (Ambien). Ambien and similar sleep medications can be effective, and they're much less likely to be habit-forming than some other drugs sometimes prescribed for sleep problems — for example, benzodiazepines, such as alprazolam (Xanax), lorazepam (Ativan) or ...
Aug 15, 2023 · It can sometimes cause a decrease in memory, confusion, and thinking issues. These side effects are more common in elders. In addition, taking Benadryl long-term might increase the risk of dementia. People aged> 65 who took medications such as Benadryl daily for over three years had an increased risk of dementia. . Cheap sofas for under dollar100
In the drug realm, antihistamines such as diphenhydramine (Benadryl), chlorpheniramine (Chlor-Trimeton), cetirizine (Zyrtec), and loratadine (Claritin) can help with a stuffy nose are safe for the heart. Nasal sprays deliver a decongestant right where you need it. In theory, this should minimize cardiovascular effects.While there are cases of misuse and abuse, withdrawal symptoms from Benadryl are rare, even with long term use. Nevertheless, Benadryl has strong anticholinergic effects, and there have been reports of 'anticholinergic withdrawal' in some individuals taking Benadryl for extended periods of time. Potential symptoms include:Feb 18, 2010 · One Benadryl per night seems to be enough to keep the ears dry & the resulting nausea at bay. I must admit that I'm not sure this is still even a problem for me. The last time I stopped to see if I still needed it was about 2 years ago. After 3 days, the dizziness/nausea/inner ear issues came back, so I promptly started taking the nightly ... Diphenhydramine, which is available as an over-the-counter medication, is a first-generation antihistamine that is used in a variety of conditions to treat and prevent dystonias, insomnia, pruritis, urticaria, vertigo, and motion sickness. It also possesses local anesthetic properties for those patients who have allergies to other, more commonly used local anesthetics; however, this is an off ...Long term use of some antihistamines may increase your risk of dementia. Diphenhydramine (Benadryl®) blocks the effects of a neurotransmitter called acetylcholine. This neurotransmitter is vital for memory and learning. Diphenhydramine increased the risk of dementia by 54% in one 3,000 patient study followed for seven years. Benadryl may cause serious side effects including: pounding heartbeats or fluttering in your chest, painful or difficult urination, little or no urination, confusion, lightheadedness, tightness in your neck or jaw, and. uncontrollable movements of your tongue. Get medical help right away, if you have any of the symptoms listed above.Nov 24, 2022 · But it has quite a long list of possible side effects. In fact, the Canadian Society of Allergy and Clinical Immunology has given serious warnings about them, even for people. The organization issued a 2019 position statement about Benadryl. They advised against the drug because of the high risk of side effects and overdose. They said the drug ... Giving Benadryl to dogs long term in some cases can be helpful for the dog. However, one of the main side effects of Benadryl is drowsiness. Giving too much dog Benadryl can cause the dog to go into a deep sleep for some time. Additionally, in some cases Benadryl can cause upset stomach and even possibly loss of appetite.Mar 21, 2023 · There is very little scientific research about the long-term effects of Benadryl. Some side effects that may occur with long-term use include: constipation; blurred vision The short answer seems to be yes. While occasionally taking a Benadryl for sleep probably won’t lead to significant weight gain, chronic use of antihistamines can interfere with weight loss efforts. If you need an antihistamine for frequent allergy symptoms, however, the best choice is Claritin because it does not cross into the brain and has ...May 13, 2021 · The active ingredient in Benadryl is called diphenhydramine. Like any medication, Benadryl has several side effects. Some of the most common are: feeling sleepy or drowsy. dry mouth or throat ... Feb 6, 2023 · Benadryl is an over-the-counter antihistamine that contains the active ingredient diphenhydramine. People often use it to treat allergies. Because it causes drowsiness, some people take it as a ... Answer From Eric J. Olson, M.D. It's unlikely you'll become dependent on zolpidem (Ambien). Ambien and similar sleep medications can be effective, and they're much less likely to be habit-forming than some other drugs sometimes prescribed for sleep problems — for example, benzodiazepines, such as alprazolam (Xanax), lorazepam (Ativan) or ...First-generation antihistamines come with an increased risk of certain side effects and drug interactions, so they are not generally advised for long-term usage. “With first-generation antihistamines, some people note decreasing effectiveness if used daily for several days,” says Dr. Lin.Common Side Effects of Diphenhydramine. Diphenhydramine is considered an H1 receptor antagonist, and it works by blocking the effect of histamine in the body. The chemical reactions that diphenhydramine trigger in the body can cause other potentially significant sedative side effects on the central nervous system (CNS).Feb 6, 2023 · Benadryl is an over-the-counter antihistamine that contains the active ingredient diphenhydramine. People often use it to treat allergies. Because it causes drowsiness, some people take it as a ... Apr 6, 2023 · Dizziness. Feeling nervous and excitable. Not able to sleep. Feeling sleepy. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https ... .
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