Apr 15, 2016 · 7. I want to specify different random effects in a model using nlme::lme (data at the bottom). The random effects are: 1) intercept and position varies over subject; 2) intercept varies over comparison. This is straightforward using lme4::lmer: lmer (rating ~ 1 + position + (1 + position | subject) + (1 | comparison), data=d) > ... Linear Mixed Effects Models. Linear Mixed Effects models are used for regression analyses involving dependent data. Such data arise when working with longitudinal and other study designs in which multiple observations are made on each subject. Some specific linear mixed effects models are. Random intercepts models, where all responses in a ...Apr 11, 2023 · Inspecting and modeling residual autocorrelation with gaps in linear mixed effects models. Here I generate a dataset where measurements of response variable y and covariates x1 and x2 are collected on 30 individuals through time. Each individual is denoted by a unique ID . c (Claudia Czado, TU Munich) – 11 – Likelihood Inference for LMM: 1) Estimation of β and γ for known G and R Estimation of β: Using (5), we have as MLE or weighted LSE of βAug 8, 2018 · 3. MIXED EFFECTS MODELS 3.1 Overview of mixed effects models When a regression contains both random and fixed effects, it is said to be a mixed effects model, or simply, a mixed model. Fixed effects are those with which most researchers are familiar. Any covariate that is assumed to have the same effect for all responses throughout the There is spatial autocorrelation in the data which has been identified using a variogram and Moran's I. The problem is I tried to run a lme model, with a random effect of the State that district is within: mod.cor<-lme(FLkm ~ Monsoon.Precip + Monsoon.Temp,correlation=corGaus(form=~x+y,nugget=TRUE), data=NE1, random = ~1|State)Gamma mixed effects models using the Gamma() or Gamma.fam() family object. Linear mixed effects models with right and left censored data using the censored.normal() family object. Users may also specify their own log-density function for the repeated measurements response variable, and the internal algorithms will take care of the optimization.Oct 31, 2016 · I'm trying to model the evolution in time of one weed species (E. crus galli) within 4 different cropping systems (=treatment). I have 5 years of data spaced out equally in time and two repetitions (block) for each cropping system. Hence, block is a random factor. Measures were repeated each year on the same block (--> repeated measure mixed ... Dear fellow Matlab users, Recently I have made good use of Matlab's built-in functions for making linear mixed effects. Currently I am trying to model time-series data (neuronal activity) from c...Linear mixed-effect model without repeated measurements. The OLS model indicated that additional modeling components are necessary to account for individual-level clustering and residual autocorrelation. Linear mixed-effect models allow for non-independence and clustering by describing both between and within individual differences.Subject. Re: st: mixed effect model and autocorrelation. Date. Sat, 13 Oct 2007 12:00:33 +0200. Panel commands in Stata (note: only "S" capitalized!) usually accept unbalanced panels as input. -glamm- (remember the dashes!), which you can download from ssc (by typing: -ssc install gllamm-), allow for the option cluster, which at least partially ...I'm trying to model the evolution in time of one weed species (E. crus galli) within 4 different cropping systems (=treatment). I have 5 years of data spaced out equally in time and two repetitions (block) for each cropping system. Hence, block is a random factor. Measures were repeated each year on the same block (--> repeated measure mixed ...1 Answer. Mixed models are often a good choice when you have repeated measures, such as here, within whales. lme from the nlme package can fit mixed models and also handle autocorrelation based on a AR (1) process, where values of X X at t − 1 t − 1 determine the values of X X at t t.Apr 11, 2023 · Inspecting and modeling residual autocorrelation with gaps in linear mixed effects models. Here I generate a dataset where measurements of response variable y and covariates x1 and x2 are collected on 30 individuals through time. Each individual is denoted by a unique ID . Chapter 10 Mixed Effects Models. Chapter 10. Mixed Effects Models. The assumption of independent observations is often not supported and dependent data arises in a wide variety of situations. The dependency structure could be very simple such as rabbits within a litter being correlated and the litters being independent. lmer (lme4) glmmTMB (glmmTMB) We will start by fitting the linear mixed effects model. data.hier.lme <- lme(y ~ x, random = ~1 | block, data.hier, method = "REML") The hierarchical random effects structure is defined by the random= parameter. In this case, random=~1|block indicates that blocks are random effects and that the intercept should be ...Mixed Models, i.e. models with both fixed and random effects arise in a variety of research situations. Split plots, strip plots, repeated measures, multi-site clinical trials, hierar chical linear models, random coefficients, analysis of covariance are all special cases of the mixed model.6 Linear mixed-effects models with one random factor. 6.1 Learning objectives; 6.2 When, and why, would you want to replace conventional analyses with linear mixed-effects modeling? 6.3 Example: Independent-samples \(t\)-test on multi-level data. 6.3.1 When is a random-intercepts model appropriate?Eight models were estimated in which subjects nervousness values were regressed on all aforementioned predictors. The first model was a standard mixed-effects model with random effects for the intercept and the slope but no autocorrelation (Model 1 in Tables 2 and 3). The second model included such an autocorrelation (Model 2).Models all contained the same fixed effects, were compared using AIC, and were fitted by REML (to allow comparison of different correlation structures by AIC). I'm using the R package nlme and the gls function. Question 1. The GLS models' residuals still display almost identical cyclical patterns when plotted against time.Is it accurate to say that we used a linear mixed model to account for missing data (i.e. non-response; technology issues) and participant-level effects (i.e. how frequently each participant used ...Autocorrelation in linear mixed models (lme) Ask Question Asked 3 years, 1 month ago Modified 3 years, 1 month ago Viewed 4k times 4 To study the diving behaviour of whales, I have a dataframe where each row corresponds to a dive (id) carried out by a tagged individual (whale).An extension of the mixed-effects growth model that considers between-person differences in the within-subject variance and the autocorrelation. Stat Med. 2022 Feb 10;41 (3):471-482. doi: 10.1002/sim.9280.Segmented linear regression models are often fitted to ITS data using a range of estimation methods [8,9,10,11]. Commonly ordinary least squares (OLS) is used to estimate the model parameters ; however, the method does not account for autocorrelation. Other statistical methods are available that attempt to account for autocorrelation in ...Autocorrelation in linear mixed models (lme) Ask Question Asked 3 years, 1 month ago Modified 3 years, 1 month ago Viewed 4k times 4 To study the diving behaviour of whales, I have a dataframe where each row corresponds to a dive (id) carried out by a tagged individual (whale).Gamma mixed effects models using the Gamma() or Gamma.fam() family object. Linear mixed effects models with right and left censored data using the censored.normal() family object. Users may also specify their own log-density function for the repeated measurements response variable, and the internal algorithms will take care of the optimization.a random effect for the autocorrelation. After introducing the extended mixed-effect location scale (E-MELS), ... mixed-effect models that have been, for example, combined with Lasso regression (e ... What is autocorrelation? Generalized Additive Mixed Effects Models have several components: Smooth terms for covariates; Random Effects: Intercepts, Slopes and Smooths. Categorical Predictors; Interactions of (1)-(3) We can add one more component for autocorrelation: modeling the residuals: Covariance structure for the residuals.Because I have 4 observations for each Site but I am not interested in this effect, I wanted to go for a Linear Mixed Model with Site as random effect. However, climatic variables are often highly spatially autocorrelated so I also wanted to add a spatial autocorrelation structure using the coordinates of the sites.The code below shows how the random effects (intercepts) of mixed models without autocorrelation terms can be extracted and plotted. However, this approach does not work when modelling autocorrelation in glmmTMB. Use reproducible example data from this question: glmmTMB with autocorrelation of irregular timesGeneralized additive models were flrst proposed by Hastie and Tibshirani (1986, 1990). These models assume that the mean of the response variable depends on an additive pre-dictor through a link function. Like generalized linear models (GLMs), generalized additive models permit the response probability distribution to be any member of the ...c (Claudia Czado, TU Munich) – 11 – Likelihood Inference for LMM: 1) Estimation of β and γ for known G and R Estimation of β: Using (5), we have as MLE or weighted LSE of βDear fellow Matlab users, Recently I have made good use of Matlab's built-in functions for making linear mixed effects. Currently I am trying to model time-series data (neuronal activity) from c...1 Answer. In principle, I believe that this would work. I would suggest to check what type of residuals are required by moran.test: deviance, response, partial, etc. glm.summaries defaults to deviance residuals, so if this is what you want to test, that's fine. But if you want the residuals on the response scale, that is, the observed response ...c (Claudia Czado, TU Munich) – 11 – Likelihood Inference for LMM: 1) Estimation of β and γ for known G and R Estimation of β: Using (5), we have as MLE or weighted LSE of β Ultimately I'd like to include spatial autocorrelation with corSpatial(form = ~ lat + long) in the GAMM model, or s(lat,long) in the GAM model, but even in basic form I can't get the model to run. If it helps understand the structure of the data, I've added dummy code below (with 200,000 rows):Dec 24, 2014 · Is it accurate to say that we used a linear mixed model to account for missing data (i.e. non-response; technology issues) and participant-level effects (i.e. how frequently each participant used ... The “random effects model” (also known as the mixed effects model) is used when the analysis must account for both fixed and random effects in the model. This occurs when data for a subject are independent observations following a linear model or GLM, but the regression coefficients vary from person to person. Infant growth is a Eight models were estimated in which subjects nervousness values were regressed on all aforementioned predictors. The first model was a standard mixed-effects model with random effects for the intercept and the slope but no autocorrelation (Model 1 in Tables 2 and 3). The second model included such an autocorrelation (Model 2).You should try many of them and keep the best model. In this case the spatial autocorrelation in considered as continous and could be approximated by a global function. Second, you could go with the package mgcv, and add a bivariate spline (spatial coordinates) to your model. This way, you could capture a spatial pattern and even map it.3. MIXED EFFECTS MODELS 3.1 Overview of mixed effects models When a regression contains both random and fixed effects, it is said to be a mixed effects model, or simply, a mixed model. Fixed effects are those with which most researchers are familiar. Any covariate that is assumed to have the same effect for all responses throughout the1 Answer. Mixed models are often a good choice when you have repeated measures, such as here, within whales. lme from the nlme package can fit mixed models and also handle autocorrelation based on a AR (1) process, where values of X X at t − 1 t − 1 determine the values of X X at t t.Arguments. the value of the lag 1 autocorrelation, which must be between -1 and 1. Defaults to 0 (no autocorrelation). a one sided formula of the form ~ t, or ~ t | g, specifying a time covariate t and, optionally, a grouping factor g. A covariate for this correlation structure must be integer valued. When a grouping factor is present in form ...This is what we refer to as “random factors” and so we arrive at mixed effects models. Ta-daa! 6. Mixed effects models. A mixed model is a good choice here: it will allow us to use all the data we have (higher sample size) and account for the correlations between data coming from the sites and mountain ranges. The first model was a longitudinal mixed-effect model with a first-order autocorrelation structure, and the second model was the E-MELS. Both were implemented as described above. The third model was a longitudinal mixed-effect model with a Lasso penalty.Sep 16, 2018 · Recently I have made good use of Matlab's built-in functions for making linear mixed effects. Currently I am trying to model time-series data (neuronal activity) from cognitive experiments with the fitlme() function using two continuous fixed effects (linear speed and acceleration) and several, hierarchically nested categorical random factors (subject identity, experimental session and binned ... Linear mixed model fit by maximum likelihood [’lmerMod’] AIC BIC logLik deviance df.resid 22.5 25.5 -8.3 16.5 17 Random effects: Groups Name Variance Std.Dev. operator (Intercept) 0.04575 0.2139 *** Operator var Residual 0.10625 0.3260 estimate is smaller. Number of obs: 20, groups: operator, 4 Results in smaller SE for the overall Fixed ...Recently I have made good use of Matlab's built-in functions for making linear mixed effects. Currently I am trying to model time-series data (neuronal activity) from cognitive experiments with the fitlme() function using two continuous fixed effects (linear speed and acceleration) and several, hierarchically nested categorical random factors (subject identity, experimental session and binned ...Jul 9, 2023 · For a linear mixed-effects model (LMM), as fit by lmer, this integral can be evaluated exactly. For a GLMM the integral must be approximated. For a GLMM the integral must be approximated. The most reliable approximation for GLMMs is adaptive Gauss-Hermite quadrature, at present implemented only for models with a single scalar random effect. 1 discussing the implicit correlation structure that is imposed by a particular model. This is easiest seen in repeated measures. The simplest model with occasions nested in individuals with a ...In the present article, we suggested an extension of the mixed-effects location scale model that allows a researcher to include random effects for the means, the within-person residual variance, and the autocorrelation.Abstract. The ‘DHARMa’ package uses a simulation-based approach to create readily interpretable scaled (quantile) residuals for fitted (generalized) linear mixed models. Currently supported are linear and generalized linear (mixed) models from ‘lme4’ (classes ‘lmerMod’, ‘glmerMod’), ‘glmmTMB’, ‘GLMMadaptive’ and ‘spaMM ...Feb 23, 2022 · It is evident that the classical bootstrap methods developed for simple linear models should be modified to take into account the characteristics of mixed-effects models (Das and Krishen 1999). In ... PROC MIXED in the SAS System provides a very flexible modeling environment for handling a variety of repeated measures problems. Random effects can be used to build hierarchical models correlating measurements made on the same level of a random factor, including subject-specific regression models, while a variety of covariance and in nlme, it is possible to specify the variance-covariance matrix for the random effects (e.g. an AR (1)); it is not possible in lme4. Now, lme4 can easily handle very huge number of random effects (hence, number of individuals in a given study) thanks to its C part and the use of sparse matrices. The nlme package has somewhat been superseded ...In R, the lme linear mixed-effects regression command in the nlme R package allows the user to fit a regression model in which the outcome and the expected errors are spatially autocorrelated. There are several different forms that the spatial autocorrelation can take and the most appropriate form for a given dataset can be assessed by looking ...include a random subject effect when modeling the residual variance. Several authors have proposed such extensions of the mixed-effects model, with the mixed-effects location scale model by Hedeker et al6,8,9 (MELS) being among the most widely known (but see also References 10 and 11).Abstract. The ‘DHARMa’ package uses a simulation-based approach to create readily interpretable scaled (quantile) residuals for fitted (generalized) linear mixed models. Currently supported are linear and generalized linear (mixed) models from ‘lme4’ (classes ‘lmerMod’, ‘glmerMod’), ‘glmmTMB’, ‘GLMMadaptive’ and ‘spaMM ...I am seeking advice on how to effectively eliminate autocorrelation from a linear mixed model. My experimental design and explanation of fixed and random factors can be found here from an earlier question I asked: Crossed fixed effects model specification including nesting and repeated measures using glmm in RAutocorrelation in linear mixed models (lme) Ask Question Asked 3 years, 1 month ago Modified 3 years, 1 month ago Viewed 4k times 4 To study the diving behaviour of whales, I have a dataframe where each row corresponds to a dive (id) carried out by a tagged individual (whale).Sep 16, 2018 · Recently I have made good use of Matlab's built-in functions for making linear mixed effects. Currently I am trying to model time-series data (neuronal activity) from cognitive experiments with the fitlme() function using two continuous fixed effects (linear speed and acceleration) and several, hierarchically nested categorical random factors (subject identity, experimental session and binned ... This is what we refer to as “random factors” and so we arrive at mixed effects models. Ta-daa! 6. Mixed effects models. A mixed model is a good choice here: it will allow us to use all the data we have (higher sample size) and account for the correlations between data coming from the sites and mountain ranges.The nlme package allows you to fit mixed effects models. So does lme4 - which is in some ways faster and more modern, but does NOT model heteroskedasticity or (!spoiler alert!) autocorrelation. Let’s try a model that looks just like our best model above, but rather than have a unique Time slopeThis is what we refer to as “random factors” and so we arrive at mixed effects models. Ta-daa! 6. Mixed effects models. A mixed model is a good choice here: it will allow us to use all the data we have (higher sample size) and account for the correlations between data coming from the sites and mountain ranges. Aug 13, 2021 · 1 Answer. In principle, I believe that this would work. I would suggest to check what type of residuals are required by moran.test: deviance, response, partial, etc. glm.summaries defaults to deviance residuals, so if this is what you want to test, that's fine. But if you want the residuals on the response scale, that is, the observed response ... Mixed-effects models allow multiple levels of variability; AKA hierarchical models, multilevel models, multistratum models; Good references on mixed-effects models: Bolker [1–3] Gelman & Hill [4] Pinheiro & Bates [5].Dear fellow Matlab users, Recently I have made good use of Matlab's built-in functions for making linear mixed effects. Currently I am trying to model time-series data (neuronal activity) from c...Dec 11, 2017 · Mixed-effect linear models. Whereas the classic linear model with n observational units and p predictors has the vectorized form. where and are design matrices that jointly represent the set of predictors. Random effects models include only an intercept as the fixed effect and a defined set of random effects. Chapter 10 Mixed Effects Models. Chapter 10. Mixed Effects Models. The assumption of independent observations is often not supported and dependent data arises in a wide variety of situations. The dependency structure could be very simple such as rabbits within a litter being correlated and the litters being independent.Chapter 10 Mixed Effects Models. Chapter 10. Mixed Effects Models. The assumption of independent observations is often not supported and dependent data arises in a wide variety of situations. The dependency structure could be very simple such as rabbits within a litter being correlated and the litters being independent.a random effect for the autocorrelation. After introducing the extended mixed-effect location scale (E-MELS), ... mixed-effect models that have been, for example, combined with Lasso regression (e ... Growth curve models (possibly Latent GCM) Mixed effects models. 이 모두는 mixed model 의 다른 종류를 말한다. 어떤 용어들은 역사가 깊고, 어떤 것들은 특수 분야에서 자주 사용되고, 어떤 것들은 특정 데이터 구조를 뜻하고, 어떤 것들은 특수한 케이스들이다. Mixed effects 혹은 mixed ... 7. I want to specify different random effects in a model using nlme::lme (data at the bottom). The random effects are: 1) intercept and position varies over subject; 2) intercept varies over comparison. This is straightforward using lme4::lmer: lmer (rating ~ 1 + position + (1 + position | subject) + (1 | comparison), data=d) > ...To do this, you would specify: m2 <- lmer (Obs ~ Day + Treatment + Day:Treatment + (Day | Subject), mydata) In this model: The intercept if the predicted score for the treatment reference category at Day=0. The coefficient for Day is the predicted change over time for each 1-unit increase in days for the treatment reference category.of freedom obtained by the same method used in the most recently fit mixed model. If option dfmethod() is not specified in the previous mixed command, option small is not allowed. For certain methods, the degrees of freedom for some linear combinations may not be available. See Small-sample inference for fixed effects in[ME] mixed for more ...This example will use a mixed effects model to describe the repeated measures analysis, using the lme function in the nlme package. Student is treated as a random variable in the model. The autocorrelation structure is described with the correlation statement. You need to separately specify the intercept, the random effects, the model matrix, and the spde. The thing to remember is that the components of part 2 of the stack (multiplication factors) are related to the components of part 3 (the effects). Adding an effect necessitates adding another 1 to the multiplication factors (in the right place).Eight models were estimated in which subjects nervousness values were regressed on all aforementioned predictors. The first model was a standard mixed-effects model with random effects for the intercept and the slope but no autocorrelation (Model 1 in Tables 2 and 3). The second model included such an autocorrelation (Model 2). Jul 1, 2021 · Mixed Effects Models - Autocorrelation. Jul. 1, 2021 • 0 likes • 171 views. Download Now. Download to read offline. Education. Lecture 19 from my mixed-effects modeling course: Autocorrelation in longitudinal and time-series data. Scott Fraundorf Follow. Here's a mixed model without autocorrelation included: cmod_lme <- lme(GS.NEE ~ cYear, data=mc2, method="REML", random = ~ 1 + cYear | Site) and you can explore the autocorrelation by using plot(ACF(cmod_lme)) .1 Answer. Mixed models are often a good choice when you have repeated measures, such as here, within whales. lme from the nlme package can fit mixed models and also handle autocorrelation based on a AR (1) process, where values of X X at t − 1 t − 1 determine the values of X X at t t.Growth curve models (possibly Latent GCM) Mixed effects models. 이 모두는 mixed model 의 다른 종류를 말한다. 어떤 용어들은 역사가 깊고, 어떤 것들은 특수 분야에서 자주 사용되고, 어떤 것들은 특정 데이터 구조를 뜻하고, 어떤 것들은 특수한 케이스들이다. Mixed effects 혹은 mixed ...Mar 29, 2021 · Ultimately I'd like to include spatial autocorrelation with corSpatial(form = ~ lat + long) in the GAMM model, or s(lat,long) in the GAM model, but even in basic form I can't get the model to run. If it helps understand the structure of the data, I've added dummy code below (with 200,000 rows): This example will use a mixed effects model to describe the repeated measures analysis, using the lme function in the nlme package. Student is treated as a random variable in the model. The autocorrelation structure is described with the correlation statement. What is autocorrelation? Generalized Additive Mixed Effects Models have several components: Smooth terms for covariates; Random Effects: Intercepts, Slopes and Smooths. Categorical Predictors; Interactions of (1)-(3) We can add one more component for autocorrelation: modeling the residuals: Covariance structure for the residuals. $\begingroup$ it's more a please check that I have taken care of the random effects, autocorrelation, and a variance that increases with the mean properly. $\endgroup$ – M.T.West Sep 22, 2015 at 12:15Eight models were estimated in which subjects nervousness values were regressed on all aforementioned predictors. The first model was a standard mixed-effects model with random effects for the intercept and the slope but no autocorrelation (Model 1 in Tables 2 and 3). The second model included such an autocorrelation (Model 2).Because I have 4 observations for each Site but I am not interested in this effect, I wanted to go for a Linear Mixed Model with Site as random effect. However, climatic variables are often highly spatially autocorrelated so I also wanted to add a spatial autocorrelation structure using the coordinates of the sites.
GLM, generalized linear model; RIS, random intercepts and slopes; LME, linear mixed-effects model; CAR, conditional autoregressive priors. To reduce the number of explanatory variables in the most computationally demanding of the analyses accounting for spatial autocorrelation, an initial Bayesian CAR analysis was conducted using the CARBayes .... Elastic waist dress pants women
I am seeking advice on how to effectively eliminate autocorrelation from a linear mixed model. My experimental design and explanation of fixed and random factors can be found here from an earlier question I asked: Crossed fixed effects model specification including nesting and repeated measures using glmm in RSubject. Re: st: mixed effect model and autocorrelation. Date. Sat, 13 Oct 2007 12:00:33 +0200. Panel commands in Stata (note: only "S" capitalized!) usually accept unbalanced panels as input. -glamm- (remember the dashes!), which you can download from ssc (by typing: -ssc install gllamm-), allow for the option cluster, which at least partially ... 3. MIXED EFFECTS MODELS 3.1 Overview of mixed effects models When a regression contains both random and fixed effects, it is said to be a mixed effects model, or simply, a mixed model. Fixed effects are those with which most researchers are familiar. Any covariate that is assumed to have the same effect for all responses throughout theZuur et al. in \"Mixed Effects Models and Extensions in Ecology with R\" makes the point that fitting any temporal autocorrelation structure is usually far more important than getting the perfect structure. Start with AR1 and try more complicated structures if that seems insufficient.A comparison to mixed models. We noted previously that there were ties between generalized additive and mixed models. Aside from the identical matrix representation noted in the technical section, one of the key ideas is that the penalty parameter for the smooth coefficients reflects the ratio of the residual variance to the variance components for the random effects (see Fahrmeier et al ...Aug 13, 2021 · 1 Answer. In principle, I believe that this would work. I would suggest to check what type of residuals are required by moran.test: deviance, response, partial, etc. glm.summaries defaults to deviance residuals, so if this is what you want to test, that's fine. But if you want the residuals on the response scale, that is, the observed response ... Mixed Models, i.e. models with both fixed and random effects arise in a variety of research situations. Split plots, strip plots, repeated measures, multi-site clinical trials, hierar chical linear models, random coefficients, analysis of covariance are all special cases of the mixed model. Mixed Models (GLMM), and as our random effects logistic regression model is a special case of that model it fits our needs. An overview about the macro and the theory behind is given in Chapter 11 of Littell et al., 1996. Briefly, the estimating algorithm uses the principle of quasi-likelihood and an approximation to the likelihood function of ...Eight models were estimated in which subjects nervousness values were regressed on all aforementioned predictors. The first model was a standard mixed-effects model with random effects for the intercept and the slope but no autocorrelation (Model 1 in Tables 2 and 3). The second model included such an autocorrelation (Model 2). Apr 12, 2018 · Here's a mixed model without autocorrelation included: cmod_lme <- lme(GS.NEE ~ cYear, data=mc2, method="REML", random = ~ 1 + cYear | Site) and you can explore the autocorrelation by using plot(ACF(cmod_lme)) . Dec 12, 2022 · It is a linear mixed model, with log-transformed OM regressed on marsh site (categorical), marsh type (categorical), soil category (categorical), depth (numerical, based on ordinal depth ranges), and the interaction between depth and marsh type; marsh site effects are modeled as random, on which the ICAR spatial autocorrelation structure is ... Mixed Models, i.e. models with both fixed and random effects arise in a variety of research situations. Split plots, strip plots, repeated measures, multi-site clinical trials, hierar chical linear models, random coefficients, analysis of covariance are all special cases of the mixed model. .